Generate the maximum information possible from criminal casework samples

Criminal Casework

The Illumina forensic genomics solution generates the maximum information possible from criminal casework samples. Next-generation sequencing (NGS) allows crime laboratories to simultaneously analyze every locus currently in use, plus hundreds more, from less than 1 nanogram of sample.

Starting in the 1980s, forensics labs began using DNA testing to help decipher criminal cases that were previously unsolvable. Because DNA testing can be used to exclude suspected individuals, it has become an indispensable tool.

In forensic genomics laboratories worldwide, challenging DNA samples are sometimes interrogated multiple times in an attempt to extract a full set of data. This testing might include autosomal short tandem repeat (STR) analysis, mitochondrial DNA (mtDNA) sequencing, Y-STRs, and single nucleotide polymorphisms (SNPs).

Labs might need to perform more than one assay using different technologies on limited quantity and/or poor quality samples. If the DNA testing is unsuccessful, the samples might be set aside as partial, inconclusive data. NGS changes the game.

Forensic DNA Testing for Criminal Casework
Developmental Validation of NGS

Learn about the advantages of targeted NGS and view the data validating the MiSeq FGx System in this Forensic Magazine article.

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Future of Forensic Genomics Article

Illumina sequencing by synthesis (SBS) technology on the MiSeq FGx Forensic Genomics System streamlines forensic casework by performing multiple tests at the same time. Using this sequencing system, crime laboratories can develop a more thorough, detailed profile from degraded, mixed, and limited DNA samples.

Targeted sequencing of forensically relevant STR and SNP loci empowers you to generate leads, even on cold cases. Our fully validated forensic NGS workflow includes a dedicated library prep kit, customized benchtop sequencing instrument, and an analytical software package to efficiently take you from sample to answer.

Click on the below to view products for each workflow step.

DNA Extraction & Quantitation

We recommend using your current DNA extraction and quantitation methods.

Library Preparation
ForenSeq DNA Signature Prep Kit

Assay approximately 200 genetic markers in a single test. Includes all reagents to prepare sequencing libraries from forensic DNA samples.

MiSeq FGx Instrument

First fully validated next-generation sequencing system for forensic genomics.

MiSeq FGx Reagent Kit

Pre-filled, ready-to-use reagent cartridges, specifically designed for the MiSeq FGx System.

ForenSeq Universal Analysis Software

Full functionality to analyze and interpret a wide range of forensic casework and database samples.

SNP & STR Analysis with NGS
Simplified SNP and STR Analysis

NGS enables genetic analysis for large numbers of globally relevant STR markers and dense SNP sets in a single test. Learn More »

Forensic DNA Databases
Forensic Profiling for DNA Databases

NGS can help labs produce high-quality forensic profiles for national DNA databases, with a faster turnaround. Learn More »

MiSeq FGx Forensic Genomics System Demonstration

Learn about the many advantages of the MiSeq FGx System in this two-part webcast series.
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MiSeq FGx Forensic Genomics System Webcast
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MPS – The Time is Now
MPS – The Time is Now

Hear from experts in the field how Massively Parallel Sequencing (MPS) is paving the way ahead and why now is the time to adopt.

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NGS for Forensic Genomics
Overview: NGS for Forensic Genomics

View an introduction to NGS and its applications for forensic genomics.

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The MiSeq FGx System
Take a Genomic Leap Forward in Forensic Science

The MiSeq FGx System is the first fully validated NGS solution designed exclusively for forensic science.

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MiSeq FGx Forensic Genomics System Brochure
MiSeq FGx Forensic Genomics System Brochure

Achieve more conclusive forensic results with one unified workflow.

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Future of Forensic Genomics
Future of Forensic Genomics

Researchers use NGS to obtain more information-rich data and answer more complex forensic questions.

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Harnessing NGS to Solve Crimes
Harnessing NGS to Solve Crimes

Criminalists use MiSeq FGx for high-resolution DNA profiling to build better forensic DNA databases.

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Recreating a Face Based on DNA
Recreating a Face Based on DNA

Researchers identify genetic variants that influence facial features to enable facial imaging from DNA.

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