Driving breakthroughs in cancer research

Accurate next-generation sequencing methods for a comprehensive view of cancer-causing mutations

Cancer Sequencing Methods

Cancer sequencing using next-generation sequencing (NGS) methods provides more information in less time compared to traditional single-gene and array-based approaches. With NGS, researchers can perform whole-genome studies, targeted gene profiling, tumor-normal comparisons, and more. NGS also offers the sensitivity to detect rare somatic variants, tumor subclones, and circulating DNA fragments.

Oncology
Cancer Whole-Genome Sequencing

See a comprehensive view of the unique mutations present in tumor tissue.

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Cancer Exome Sequencing

Cost-effectively identify cancer-associated coding variants.

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Targeted Cancer Sequencing

Focus on sequencing a set of genes or genomic regions with known cancer associations.

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Cancer RNA Sequencing

Identify novel transcripts or determine which genes are overexpressed or underexpressed in tumors.

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Circulating Tumor DNA (ctDNA) Sequencing

NGS offers the sensitivity and specificity that researchers need to detect low levels of ctDNA.

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Featured Cancer Sequencing Research

 
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Exploring the Genetic Basis of Oral Cancer

Researchers use various cancer sequencing methods to uncover somatic variants, methylation changes, and other genomic alterations associated with a deadly oral cancer.

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Searching for Cancer Driver Genes
Searching for Cancer Driver Gene Expression Clues

Whole-genome sequencing of ctDNA samples enables researchers to analyze nucleosome patterns and infer the gene expression status of cancer driver genes.

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Role of Long Non-Coding RNA in Cancer
Deciphering the Role of Long Non-Coding RNA in Cancer

Researchers utilize RNA sequencing to reveal how lncRNAs could be used to identify, measure, and treat cancer.

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Illumina Cancer Methods Guide

New 2021 Methods Guide for Cancer Research

Updated with new research and solutions, this comprehensive guide provides an overview of NGS-based and microarray workflows for a broad range of cancer research applications. You’ll learn about various methods and their benefits, potential applications, and step-by-step guidance through each workflow.

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Patient Success Story: Beating Stage IV Lung Cancer
Patient Success Story: Beating Stage IV Lung Cancer

AJ Patel had six months to live. Eight years later, he tells us how biomarker testing changed everything.

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Whole-exome Sequencing in Cancer Research
Whole-exome Sequencing in Cancer Research

Whole-exome sequencing on formalin-fixed, paraffin-embedded tumor tissue with Illumina DNA Prep with Enrichment

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Early Cancer Detection for Dogs is Here
Early Cancer Detection for Dogs is Here

San Diego-based molecular diagnostics company PetDx wants to help your four-legged friend

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See More Cancer-Specific Content and Products

The user-friendly "Recommended Links" feature allows you to easily find content and products relevant to cancer research and/or a variety of other fields. You can access this option from the top of any illumina.com page.

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Sequencing Limited or Low-Quality Tumor Samples

Find solutions that facilitate analysis of FFPE and limited (needle biopsy or aspirate) tumor DNA.

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Detection of Actionable Alterations in Tumors

Wagle et al. demonstrate detection of genomic alterations in tumor samples by high-throughput sequencing.

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Cancer Research Review

An overview of recent cancer research publications featuring Illumina technology.

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Cancer and Immune System Research Review

An overview of recent research publications exploring the interaction between tumor cells and the immune system.

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