In the first chapter of the series, Naomi Wray, Professor of Psychiatric and Quantitative Genetics at the University of Queensland, Gerome Breen, a geneticist at the Social Development and Psychiatry Center at King's College, London, and Yongyong Shi, a professor at the Bio-X Institute of Shanghai Jiao Tong University, explain what a polygenic risk score (PRS) is and how they’re relevant to complex diseases. Keywords: Illumina, illumina, polygenic risk score, PRS, genomics, genotyping, microarray, SNP array, genetic risk, complex disease, genetic disease, Naomi Ray, Gerome Breen, Yongyong Shi, University of Queensland, King's College, Bio-X Institute, Shanghai Jiao Tong University Subscribe to the Illumina video channel http://www.youtube.com/subscription_center?add_user=IlluminaInc A global genomics leader, Illumina provides comprehensive next-generation sequencing solutions to the research, clinical, and applied markets. Illumina technology is responsible for generating more than 90% of the world’s sequencing data.* Through collaborative innovation, Illumina is fueling groundbreaking advancements in oncology, reproductive health, genetic disease, microbiology, agriculture, forensic science, and beyond. *Data calculations on file. Illumina, Inc., 2015. View customer spotlight videos https://www.youtube.com/playlist?list=PLKRu7cmBQlajfheLzgbI4S7xBn7IDbt79 View Illumina webinars https://www.youtube.com/playlist?list=PLKRu7cmBQlahpXlnrrXlQw9itVJ8yHwUZ View Illumina product videos https://www.youtube.com/playlist?list=PLKRu7cmBQlaj6YuZmkfxZcT9twqDgP2Xd View Illumina support videos https://www.youtube.com/playlist?list=PLKRu7cmBQlajbm2KGsICWb-JOnusJfYvM