The CRISPR-Cas9 technique, which holds great promise for the future of clinical, biological, and agricultural developments, has seen many applications in 2015. This recently developed gene editing technique is a modification of the bacteria and archaea innate immune system, which greatly simplifies the targeted gene insertion, deletion, and editing in complex organisms. As the last SciMon episode for 2015, the scientific affairs team at Illumina, Inc discusses some of the recent papers that applied the CRISPR-Cas9 technique. Learn more at: http://www.illumina.com/applications/sequencing/dna_sequencing.html Products: HiSeq: http://www.illumina.com/systems/hiseq_2500_1500.html Paired-End DNA Sample Prep Kit: https://support.illumina.com/sequencing/sequencing_kits/pe_dna_sample_prep_kit.html Publication Links: Giani, et al. (2016): http://www.sciencedirect.com/science/article/pii/S1934590915004221 PMID: 26354079 | Li, et al. (2015): http://www.ncbi.nlm.nih.gov/pubmed/?term=26354079 For more information about CRISPR-Cas9: PMID: 22745249 | Jinek, et al. (2012): http://www.ncbi.nlm.nih.gov/pubmed/?term=22745249 For more information about Sequencing and CRISPR-Cas9: PMID: 24929529 | Smurnyy, et al. (2015): http://www.ncbi.nlm.nih.gov/pubmed/?term=24929529 The Science Mondays (SciMon) series is brought to you by Illumina http://www.illumina.com/ Illumina hosts Irene Predazzi, Sr Scientific Liaison, Scientific Affairs and Jacques Retief, Associate Director Scientific Affairs give you a quick report on breaking news.