Traditionally, cell and molecular biology research seeks to understand the function of a single gene, gene family, or signal transduction pathway, often through the disruption or modification of single genes. Researchers use signal-based methods such as microscopy, flow cytometry, and protein blotting and molecular assays such as PCR/qPCR, Sanger sequencing, and gene expression arrays. This approach is time-consuming and does not always result in conclusive findings.
Array and next-generation sequencing (NGS) technologies from Illumina can broaden cell and molecular biology research beyond the conventional methods of protein-interaction and single-gene functional studies. Illumina technology enables analysis across the genome, transcriptome, and epigenome. Results can inform experimental design and subsequent studies, saving time and allowing researchers to publish sooner.
Providing a high-resolution view of cell-to-cell variation for cellular and molecular biology research. This method allows you to explore the distinct biology of individual cells within a complex tissue, and understand subpopulation responses to environmental cues.Learn More
SureCell Whole Transcriptome Analysis 3' Library Prep Kit: This kit supports transcriptome profiling of hundreds to tens of thousands of single cells in a given experiment.
NextSeq 550 System: This system combines sequencing and array scanning on a single platform.
BaseSpace Sequence Hub Single-Cell RNA-Seq App: Designed for use with the SureCell WTA 3' Library Prep Kit, this app performs cell and gene counting, filtering, and reporting.
AmpliSeq for Illumina Targeted Resequencing Solution:A streamlined, scalable amplicon sequencing solution, producing high-confidence data from low-input DNA and RNA samples.
Infinium Global Screening Array: A next-generation genotyping array for population-scale genetics, variant screening, pharmacogenomics studies, and precision medicine research.
MethylationEPIC BeadChip: Robust methylation profiling microarray with extensive coverage of CpG islands, genes, and enhancers. Use for epigenome-wide association studies.