Orders of the CytoSNP-850K BeadChip with increments of 48 samples or more will now receive complimentary 8-sample BeadChip set(s) of the product. Learn More
Complimentary 8-Sample Sets of CytoSNP-850K BeadChip
To ensure our customers are successful with this Infinium product, we are offering an additional complimentary 8-sample BeadChip set with orders of 48 samples or more of the CytoSNP850K v1.2 BeadChips. This array uses a cumulative 8-sample average call rate > 0.98% and average Log R Deviation (LogRDev) < 0.20 for accurate variant detection. As a result, an individual sample could generate results outside these specifications, while still meeting the average call rate and LogRDev specifications. We have observed that, on occasion, individual samples (primarily in the row 8 BeadChip position) are outside the average call rate and LogRDev, even when the overall BeadChip average call rate and LogRDev specifications are met.
While we understand that occasional individual differences from the average specifications are not desirable for continued data analysis, we hope the extra BeadChip set(s) will help mitigate any challenges you may encounter.
Please contact your local Illumina Sales Representative for assistance in applying the complimentary CytoSNP-850K v1.2 BeadChip kits to your purchase order. Note that the additional kit(s) will not appear in your shopping cart, but will be fulfilled when we process your order.
The number of additional BeadChips provided will depend on the total number of samples ordered, as shown in the table below. There may be other combinations not displayed below that will still qualify for the additional 8-sample kits.
Type of Infinium CytoSNP-850K v1.2 BeadChip Kit Ordered
Size of Qualifying Order Required to Receive an Additional Kit
Number of Additional 8-Sample Kits Provided
6 kits or more (48 samples or more)
3 kits or more (48 samples or more)
1 kit or more (48 samples or more)
1 kit or more (48 samples or more)
Infinium CytoSNP-850K v1.2 BeadChip
This consortium-built array provides comprehensive coverage of cytogenetically relevant genes for congenital disorders and cancer research.Read More...
Match your chosen kit size to the number of samples you run at a time. Each kit is processed as a single batch and is not designed to be divided across multiple experiments. If you are processing several low-throughput batches, order multiple small kits.
The Infinium CytoSNP-850K v1.2 BeadChip is the first SNP-based human microarray to leverage the latest input from the international community for cytogenomics studies. The gene list was defined based on content from the International Collaboration for Clinical Genomics (ICCG)1 and the Cancer Genomics Consortium (CGC)2, providing a comprehensive view of cytogenomic activity.* This enhanced SNP coverage enables copy number calls as small as 10 kb in regions associated with genetic disease.
Thorough Coverage for Constitutional and Cancer Applications
The Infinium CytoSNP-850K v1.2 BeadChip provides comprehensive coverage of cytogenetically relevant genes on a proven platform, helping researchers find valuable information that may be missed by other technologies. It contains approximately 850,000 empirically selected single nucleotide polymorphisms (SNPs) spanning the entire genome with enriched coverage for 3,262 genes of known cytogenetics relevance in both constitutional and cancer applications.
High Detection Sensitivity for Low-level Mosaics
A unique attribute of the Infinium array technology is the use of long 50-mer probes that have high specificity to the SNP target. This increases sensitivity for low-level mosaics3 and offers high resolution for copy-neutral loss of heterozygosity (LOH). In addition, each SNP is represented in at least 15x redundancy to increase the signal-to-noise ratio for making accurate copy number variation (CNV) and absence of heterozygosity (AOH) calls across the genome. As few as 10 consecutive probes are necessary to make accurate CNV calls, demonstrating the high performance level of the Infinium assay.