| DRAGEN Demultiplexing |
Rapid demultiplexing of NGS analysis |
N/A |
N/A |
|---|
| DRAGEN Compression |
DRAGEN ORA compression is optimized for high compression ratios of FASTQ files, as well as rapid compression and decompression, all while preserving data integrity. |
N/A |
- Compression Ratio
- Run Time
|
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| DRAGEN Map + Align |
The DRAGEN Map + Align can be run as a standalone or as part of DRAGEN’s suite of pipelines |
N/A |
- Mapping metrics
- Duration Metrics
- Coverage Metrics
|
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| DRAGEN Germline |
The DRAGEN Germline Pipeline provides end-to-end NGS analysis, including advanced error model calibration for increased accuracy, and repeat expansion detection and genotyping through Illumina Expansion Hunter. |
- SNV
- CNV
- SV
- Repeat Expansions
|
- Mapping metrics
- Duration Metrics
- Coverage Metrics
- Variant Metrics
- Callability Report
|
|---|
| DRAGEN Somatic |
The DRAGEN Somatic Pipeline includes tumor-only and tumor–normal modes, designed for detecting somatic variants in tumor samples. Both modes make no ploidy assumptions, enabling detection of low-frequency alleles. |
|
- Mapping metrics
- Duration Metrics
- Coverage Metrics
- Variant Metrics
- Callability Report
|
|---|
| DRAGEN Enrichment |
The DRAGEN Enrichment Pipeline combines DRAGEN’s germline and somatic callers into a pipeline designed specifically for analyzing enrichment samples. Includes a full suite of enrichment metrics and reporting. |
|
- Mapping metrics
- Duration Metrics
- Coverage Metrics
- Variant Metrics
- Callability Report
|
|---|
| DRAGEN RNA |
The DRAGEN RNA Pipeline performs transcriptome analysis starting with splice junction discovery and alignment, followed by rapid alignment and splice junction mapping and quantification. For differential expression, Illumina recommends the DRAGEN Differential Expression app on BaseSpace Sequence Hub. |
|
- Mapping metrics
- Duration Metrics
- Coverage Metrics
- Variant Metrics
- Callability Report
|
|---|
| DRAGEN Single Cell RNA |
The DRAGEN Single Cell RNA pipeline performs demultiplexing, cell-barcode and UMI error correction, sequence alignment, and quantification of gene expression. |
N/A |
- Mapping Metrics
- Duration Metrics
- Coverage Metrics
- Callability Report
- Cell Metrics
|
|---|
| DRAGEN Joint Genotyping |
The DRAGEN Joint Genotyping/Population Pipeline calls variants jointly across multiple genomes and scales to large cohorts of samples at expedited speeds with uncompromising accuracy. |
- SNV
- CNV
- SV
- Repeat Expansions
|
- Mapping metrics
- Duration Metrics
- Coverage Metrics
- Variant Metrics
- Callability Report
|
|---|
| DRAGEN Methylation |
The DRAGEN Methylation Pipeline performs alignment, methyl calling, and calculates alignment and methylation metrics. |
N/A |
- Mapping metrics
- Duration Metrics
- Coverage Metrics
- Variant Metrics
- Callability Report
|
|---|
| DRAGEN Reference Builder |
Accepts FASTA files, and builds the proprietary reference used by the DRAGEN apps. |
N/A |
N/A |
|---|
| DRAGEN TruSight Oncology 500 ctDNA Analysis Software |
Secondary analysis support for Illumina’s TruSight Oncology 500 ctDNA. Only available on the local DRAGEN Server (version 3) |
- SNV
- CNV
- DNA fusions
- MSI
- TMB
|
- Mapping metrics
- Duration Metrics
- Coverage Metrics
- Variant Metrics
- Callability Report
|
|---|
| DRAGEN Imputation |
The DRAGEN Imputation pipeline is an end to end user friendly tool that enables scalable low pass whole genome sequencing analysis |
N/A |
Impute ≤100 samples simultaneously 1.7x faster compared to original GLIMPSE code |
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