NIPT - Accurate information for your patients

Reliable, easy, and fast

NIPT for Health Care Professionals

The verifi Prenatal Test is a noninvasive prenatal test that screens for multiple fetal chromosomal aneuploidies using one tube of maternal blood. The test offers the following benefits:

  • Accurate - Lowest failure rate (0.1%)
  • Reliable - Directly analyzes cell-free fetal and maternal DNA; High detection rate
  • Easy - Noninvasive blood draw, just one tube (7–10 ml); test as early as 10 weeks gestational age (8 weeks of fetal age as determined by date of conception) with no limitations regarding ethnicity, BMI, ART or egg donor cases
  • Fast - Results reported to partner laboratory in 3 - 5 business days after sample receipt (time to report may vary based on partner laboratory providing the test)
The Forefront of First Trimester Genetics

How the Process Works

Our verifi NIPT service makes the process seamless – for you and your patient.

Offering your patients the verifi Prenatal Test is easy. Our verifi NIPT service provides the test through regional, reference, and some select national laboratories. These partners send their samples to an Illumina CLIA lab for processing and then reports are sent back to the labs.

Physician recommends and orders test for patient.

Requisition and Informed Consent forms are completed, patient proceeds to blood draw.

Blood sample and test request form are sent back to lab.

Lab processes and analyzes the sample.

Test results are sent to health care professional.

Our focus on maternal and fetal health affects everything we do to help you provide the optimal care for your patient.

Genetic counselors

An in-house group of genetic counselors is available to provide guidance on laboratory results.

Laboratory directors

Experienced directors manage our state-of-the-art, CAP-accredited, CLIA-certified laboratory.

Client services

The Client Services group is on-site and readily available to provide helpful, timely support.

Educational support

Illumina is proud to support CME and other educational programs for health care professionals.

More insurers now see the value of this test. As a result, more patients will be able to obtain the test at a low cost through their insurance plans. The best way to confirm if the test is covered by a particular insurance plan is to have patients ask their insurance providers.

Trisomy 21 - Trisomy 21 (also called Down syndrome) occurs when three copies of chromosome 21 are present instead of two. People with Down Syndrome usually have intellectual disabilities that can range from mild to severe. Physically, they frequently have low muscle tone and may have heart defects. They may have a shorter lifespan. But, since every person with Down Syndrome is a unique individual, not everyone with the condition will have all of the same features.

Trisomy 18 - Trisomy 18 (also called Edwards syndrome) occurs when three copies of chromosome 18 are present instead of two. People with trisomy 18 have severe intellectual disabilities and birth defects affecting multiple organs. Few babies born with trisomy 18 survive their first year of life.

Trisomy 13 - Trisomy 13 (also called Patau syndrome) occurs when three copies of chromosome 13 are present instead of two. People with trisomy 13 have severe intellectual disabilities and birth defects affecting multiple organs. Few babies born with trisomy 13 survive their first year of life.

Monosomy X - Monosomy X (also called Turner syndrome) occurs when only one sex chromosome (the X chromosome) is present, and the second sex chromosome is missing. 1-1.5% of all pregnancies have Monosomy X. About 99% of these pregnancies will miscarry. About 1 out of every 2000 live born females has monosomy X. Common features of monosomy X include heart defects and hormone problems which can lead to shorter than average height, delayed puberty and infertility.

Triple X Syndrome (XXX) - 47,XXX occurs in about 1 in every 1,000 female live births. Many females with 47,XXX do not have any noticeable characteristics. Variable characteristics of 47,XXX include taller than average height, learning difficulties, speech, and language delays. Delayed development of motor skills and behavioral and emotional difficulties are also possible.

Klinefelter syndrome (47,XXY) - Klinefelter syndrome occurs in approximately 1 in every 500 to 1,000 male live births. Variable characteristics of Klinefelter syndrome include speech and/or learning difficulties, tall stature and small testes.

Jacob’s syndrome (47,XYY) - 47,XYY occurs in approximately 1 in every 1,000 male live births. Variable characteristics of 47,XYY include delayed development of speech and language skills, learning disabilities and autism spectrum disorders.

Trisomy 9 - A rare chromosome condition with the vast majority of instances resulting in miscarriage in the 1st trimester. While the majority of live births will not survive the newborn period, those that do will have serious health concerns, which often include intellectual disability and heart defects. Most of the cases that survive, are likely to be mosaic trisomy 9.

Trisomy 16 - The most commonly occurring autosomal trisomy seen in first trimester miscarriages. Rare survivors with mosaic trisomy 16 or trisomy 16 confined placental mosaicism (CPM) are at increased risk for health concerns including intra-uterine growth restriction, intellectual disability, and heart defects.

Microdeletions - Microdeletions are chromosome disorders caused by small missing pieces of chromosome material. They cannot usually been seen by routine methods of chromosome analysis. Microdeletions can occur on any of the 23 pairs of chromosomes. Some occur more commonly in a specific area of a particular chromosome and have been linked to known genetic syndromes. Most occur by chance, rather than being inherited from a parent, and can occur with no prior family history and without other risk factors (e.g. advanced parental age).

22q11.2 syndrome – 22q11.2 syndrome (also called DiGeorge syndrome, Velocardiofacial syndrome) affects approximately one out of every 4,000 live births. Signs and symptoms are variable but it can be associated with learning problems, congenital heart defects, incomplete fusion of the palate (cleft palate). Life expectancy is usually normal.

1p36 deletion syndrome – 1p36 deletion syndrome affects approximately one out of every 4,000 to 10,000 live births and is associated with characteristic facial features, seizures, and brain and heart defects. Intellectual disability is variable. Life expectancy is variable but can be normal.

Angelman syndrome* – Angelman syndrome (also called 15q11.2 deletion syndrome) affects approximately one out of every 12,000 live births. Features of Angelman syndrome include intellectual disability, speech problems, and seizures. Life expectancy is usually normal.

Prader-Willi syndrome* – Prader-Willi syndrome (also called 15q11.2 deletion syndrome) affects approximately one out of every 10,000–25,000 live births and is associated with low muscle tone, morbid obesity, delayed motor and language skills, intellectual disability, and small testes. Life expectancy is variable, but usually normal.

Wolf-Hirschhorn syndrome (4p- syndrome) - Wolf-Hirschhorn syndrome (also called 4p- syndrome) affects approximately one out of every 50,000 live births. Features include growth deficiency, low muscle tone, facial features, intellectual disability, and heart and brain problems. Life expectancy varies.

Cri du Chat syndrome (5p- syndrome) – Cri du Chat syndrome (also called 5p-syndrome) affects approximately one out of every 20,000–50,000 live births. Features include intellectual disability, speech delay, and a ‘cat-like’ cry. About 10% of babies will not survive the first year of life; for the 90% that survive, life expectancy varies but is usually normal.

*The microdeletion region is the same region for Angelman and Prader-Willi syndromes (15q11.2). NIPT will not distinguish between these two syndromes. Further testing is necessary.
Fetal sex will only be reported if the sex chromosomes option is ordered. If the sex chromosomes option is ordered, and no sex chromosome aneuploidies are detected, the result is reported as either XX or XY. It is for the health care professional and patient to decide if the fetal sex information is to be revealed to the patient.
No. Fetal sex is only analyzed when the sex chromosomes option is ordered. This option includes 6 analysis categories (XX, XY, XXY, XXX, XYY, and Monosomy X). There is no option to request testing for only fetal sex analysis with the verifi prenatal test.
The verifi Prenatal Test will remain for chromosomes 21, 18, and 13. The sex chromosome option is an optional second check on the test request form.
No. There is no additional cost for the sex chromosome option and it takes the same amount of time to report results. The results are usually reported to the ordering provider within 3–5 business days after sample receipt. However, the time to report may vary based on the partner laboratory providing the test. Please refer to the partner’s website for accurate estimate of turnaround time.
The microdeletion option tests for a number of disorders and T9 and T16 (see above). Check the box to order this option.
Our Laboratory Partners

Our network of reliable partners offer the verifi Prenatal Test. They can also offer services to further enhance the patient and physician experience.

View Laboratory Partner List
Laboratory Partners List



The verifi Prenatal Test was developed by, and its performance characteristics were determined by Verinata Health, Inc. a wholly owned subsidiary of Illumina, Inc. The VHI laboratory is CAP-accredited and certified under the Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high complexity clinical laboratory testing. It has not been cleared or approved by the U.S. Food and Drug Administration.