Individual lane loading with the NovaSeq Xp workflow allows you to sequence multiple library pools within each NovaSeq flow cell lane. This optional workflow offers an alternative to standard onboard cluster generation on the NovaSeq 6000 System. With the NovaSeq Xp workflow, you can:
The NovaSeq Xp workflow offers the flexibility to load each flow cell lane independently. Labs can now multiplex samples within each lane, maximizing the total number of samples per flow cell. This high degree of multiplexing also reduces the required DNA input compared to the standard workflow.
The NovaSeq Xp workflow is compatible with both manual flow cell lane loading and automated loading using liquid-handling robots.