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TruSight Oncology 500 Portfolio

TruSight Oncology 500アッセイ

自動化対応キットを新たに発売し、FFPE検体からDNAとRNA両方のがんバイオマーカーを解析します。

TruSight Oncology 500 High-Throughputアッセイ

TruSight Oncology 500アッセイ同様、組織検体から同じバイオマーカーを検出し、一回192サンプルまで解析できます。

TruSight Oncology 500 ctDNA アッセイ

血漿検体から血中ctDNAを対象に、TruSight Oncology 500アッセイのDNAパネルと同じ遺伝子を解析します。

Pan-Cancer Biomarkers

Detection of currently relevant DNA & RNA variants for multiple types of cancer.
Some key biomarkers include:
Pan-Cancer Biomarkers      NTRK1        NTRK2        NTRK3        MSI        TMB
Lung Melanoma Colon Ovarian Breast Gastric Bladder Sarcoma
AKT1 BRAF AKT1 BRAF AKT1 BRAF MSH5 ALK
ALK CTNNB1 BRAF BRCA1 AR KIT PMS2 APC
BRAF GNA11 HRAS BRCA2 BRCA1 KRAS TSC1 BRAF
DDR2 GNAQ KRAS KRAS BRCA2 MET   CDK4
EGFR KIT MET PDGFRA ERBB2 MLH1   CTNNB1
ERBB2 MAP2K1 MLH1 FOXL2 FGFR1 PDGFRA   ETV6
FGFR1 NF1 MSH2 TP53 FGFR2 TP53   EWSR1
FGFR3 NRAS MSH6   PIK3CA     FOXO1
KRAS PDGFRA NRAS   PTEN     GLI1
MAP2K1 PIK3CA PIK3CA         KJT
MET PTEN PMS2         MDM2
NRAS TP53 PTEN         MYOD1
PIK3CA   SMAD4         NAB2
PTEN   TP53         NF1
RET             PAX3
TP53             PAX7
              PDGFRA
              PDGFRB
              SDHB
              SDHC
              SMARCB1
              TFE3
              WT1

The genes and biomarkers listed in this table are a subset of all genes included in the panel. To see the full gene list, view the product datasheet, available under Product Literature on the respective product pages.

Illumina NGS Methods Guide

Analytical Evaluation & Verification Service

The TruSight Oncology 500 Analytical Evaluation Service facilitates alignment with the latest CAP, AMP, and European standards. Use the service to evaluate analytical performance characteristics and integrate products into your workflows while reducing overall evaluation time by ~60%.

View Service

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