がんを不透明なものから
理解できるものに

製品ポートフォリオの拡充により、血液と組織検体、
両方から包括的ゲノムプロファイリングが可能に

TruSight Oncology 500製品ファミリー

TruSight Oncology 500製品ファミリーは、施設内で血液と組織検体両方からの包括的ゲノムプロファイリングを実現します。このファミリーに含まれる3つのアッセイはすべて既存および注目されているがんバイオマーカーを検出するように設計されています。

  TruSight Oncology 500 TruSight Oncology 500 High-Throughput TruSight Oncology 500 ctDNA
Sample Type FFPE (DNA and RNA) FFPE (DNA and RNA) Plasma (cfDNA)
Gene Content 523 cancer-relevant genes from both DNA for analysis of SNV and small Indel and 55 genes from from RNA for analysis of fusions and splice variants 523 cancer-relevant genes from both DNA for analysis of SNV and small Indel and 55 genes from from RNA for analysis of fusions and splice variants 523 cancer-relevant genes for DNA for analysis of SNV and small Indel
Genes to call CNV 59 Genes 59 Genes 59 Genes
Fusions 55 genes 55 genes 23 genes
MSI loci 130 loci 130 loci 76 loci
Sequencing Coverage 3,500x 3,500x 35,000x
Panel size 1.94 Mb DNA
358 kb RNA
1.94 Mb DNA
358 kb RNA
1.94 Mb DNA
Sequencing Platform NextSeq 550Dx (Research mode)
NextSeq 500/550
NovaSeq 6000 NovaSeq 6000
Sample Throughput NextSeq - 8 NovaSeq SP - 16
NovaSeq S1 - 32
NovaSeq S2 - 72
NovaSeq S4 - 192
NovaSeq S2 - 8
NovaSeq S4 - 24
Indexing Capability 16 UD TruSight Indexes (DNA and RNA) 192 IDT for illumina Nextera DNA UD Indexes (DNA and RNA) 16 UD TruSight indexes (DNA)
Sample Input 40 ng DNA
40 ng RNA
40 ng DNA
40-80 ng RNA
30 ng cfDNA
Specificity (SNV Detection) 99.9998% 99.9998% 99.9995%
Sensitivity >96% >96% >95%

TruSight Oncology 500製品ファミリー

Analytical Evaluation & Verification Service

The TruSight Oncology 500 Analytical Evaluation Service is a set of tools intended to guide you in aligning with the latest CAP, AMP, and European standards. We provide recommendations to help you evaluate analytical performance characteristics and integrate products into your workflows.

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Illumina NGS Methods Guide
Liquid Biopsy Offers Advantages in the Modern Age
Liquid Biopsy Offers Advantages in the Modern Age

Innovations in molecular assays enable comprehensive, precise analysis of cell-free DNA.

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Findings from Early Access Program
Findings from Early Access Program

The next step in precision medicine lies in decentralizing comprehensive biomarker testing.

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Findings from Early Access Program
TruSight Oncology 500 and TruSight Oncology 500 High-Throughput

Enabling comprehensive genomic profiling from FFPE samples, with flexibility and scalability.

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Findings from Early Access Program
TruSight Oncology 500 ctDNA Data Sheet

A liquid biopsy assay that enables comprehensive genomic profiling, including TMB and MSI, from plasma.

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The Power and Promise of Liquid Biopsies

Dr. Phil Febbo, Chief Medical Officer at Illumina, shares why he’s enthusiastic about liquid biopsies.

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TruSight Oncology 500 Selected to Power Liquid Biopsy Studies

Illumina and the Frederick National Laboratory are working together to establish clinical utility for liquid biopsies.

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The Unifying Force Has Arrived

TruSight Oncology 500 products offer deep, comprehensive, and accessible sequencing power for detecting tumor biomarkers.

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イルミナの製品についてご質問があれば下記フォームからお問い合わせください。担当者からご連絡します。
Cancer RNA Sequencing

RNA-Seq provides functional information about gene expression and the gene fusions that drive tumor progression.

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Automation Solutions

Various leading vendors have developed automation methods for Illumina library prep, including TruSight Oncology 500 products.

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Circulating Tumor DNA Sequencing

Next-generation sequencing offers the sensitivity and specificity to detect low levels of ctDNA in the bloodstream.

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TruSight Hereditary Cancer Panel
TruSight Hereditary Cancer Panel

Expert-defined content targeting 113 genes associated with genetic cancer risk predisposition.

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TruSight Tumor 15
TruSight Tumor 15

Focused sequencing panel to assess 15 genes that are commonly mutated in solid tumors in a single assay, with a simple, rapid workflow.

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TruSight Myeloid Sequencing Panel
TruSight Myeloid Sequencing Panel

This sequencing research panel targets variants associated with myeloid malignancies such as AML, MDS, MPN, CML, CMML, and JMML.

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AmpliSeq for Illumina BRCA Panel
AmpliSeq for Illumina BRCA Panel

Targeted research panel investigating somatic and germline variants in BRCA1 and BRCA2.

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AmpliSeq for Illumina Cancer Hotspot Panel v2
AmpliSeq for Illumina Cancer Hotspot Panel v2

Targeted research panel investigating hotspot regions of 50 genes with known associations to cancer.

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TruSight RNA Fusion Panel
TruSight RNA Fusion Panel

Provides comprehensive gene fusion detection in formalin-fixed, paraffin-embedded (FFPE) and other cancer research samples.

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