TruSight Oncology 500 High-Throughput

FFPEサンプルから、フローセルあたり一回192サンプルまで解析できる新たな柔軟性を備え、包括的なゲノムプロファイリングを実現します。 続きを読む...

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What Products do I need?
Manual Prep

TruSight Oncology 500 DNA High-Throughput Kit (48 Samples)

20040765

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TruSight Oncology 500 DNA High-Throughput Kit (144 Samples)

20040767

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TruSight Oncology 500 DNA/RNA High-Throughput Kit (24 Samples)

20040764

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TruSight Oncology 500 DNA/RNA High-Throughput Kit (72 Samples)

20040766

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TruSight Oncology 500 DNA/RNA High-Throughput Kit (24 Samples), plus Pierian

20040768

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TruSight Oncology 500 DNA High-Throughput Kit (48 Samples), plus Pierian

20040769

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TruSight Oncology 500 DNA/RNA High-Throughput Kit (72 Samples), plus Pierian

20040770

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TruSight Oncology 500 DNA High-Throughput Kit (144 Samples), plus Pierian

20040771

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Automation

TruSight Oncology 500 High-Throughput DNA for Automation (64 Samples)

20049283

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TruSight Oncology 500 High-Throughput DNA/RNA for Automation (32 Samples)

20049282

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TruSight Oncology 500 High-Throughput DNA for Automation (64 Samples), Plus Pierian

20049277

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TruSight Oncology 500 High-Throughput DNA/RNA for Automation (32 Samples), Plus Pierian

20049276

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TruSight Oncology 500 High-Throughput DNA for Automation (144 Samples)

20049285

価格
 
 

TruSight Oncology 500 High-Throughput DNA for Automation (144 Samples), Plus Pierian

20049279

価格
 
 

TruSight Oncology 500 High-Throughput DNA/RNA for Automation (72 Samples)

20049284

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TSO500 DNA/RNA HT Auto (72 spls) + Pierian

20049278

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Index Adapters

IDT® for Illumina® UMI DNA/RNA UD Indexes Set A, Ligation (96 Indexes, 96 Samples)

20034701

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IDT® for Illumina® UMI DNA/RNA UD Indexes Set B, Ligation (96 Indexes, 96 Samples)

20034702

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IDT for Illumina UMI DNA/DNA Index Anchors Set A for Automation

20066404

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IDT for Illumina UMI DNA/RNA Index Anchors Set B for Automation

20063213

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Reagents

NovaSeq 6000 S4 Reagent Kit v1.5 (200 cycles)

20028313

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NovaSeq 6000 S2 Reagent Kit v1.5 (200 cycles)

20028315

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NovaSeq 6000 S1 Reagent Kit v1.5 (200 cycles)

20028318

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NovaSeq 6000 SP Reagent Kit v1.5 (200 cycles)

20040719

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Services

Trusight Oncology 500 HT Training (DNA) - Customer Site

20042220

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Trusight Oncology 500 HT Training (DNA and RNA) - Customer Site

20042219

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Software and Informatics Options

Illumina DRAGEN Server v3

20040619

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Illumina DRAGEN Server v4

20051343

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ICA Basic Annual Subscription

20044874

ICA Professional Annual Subscription

20044876

ICA Enterprise Annual Subscription

20038994

ICA Enterprise Service and Compliance Add-on (applies to Basic only)

20066830

Illumina Analytics - 1 iCredit

20042038

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Illumina Analytics Starter Package - 1,000 iCredits

20042039

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Illumina Analytics - 5,000 iCredit

20042040

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Illumina Analytics - 50,000 iCredit

20042041

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Illumina Analytics - 100,000 iCredit

20042042

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製品のハイライト

The TruSight Oncology 500 High-Throughput assay is built on the foundation of the TruSight Oncology 500 assay, with flexibility for higher sample throughput and batching options.

Consolidate Multiple Biomarker Assays into One

  • Pan-cancer biomarker content aligned with key guidelines and clinical trials
  • DNA + RNA assay targeting 523 genes for assessment of all DNA and RNA variant types, plus MSI and TMB
  • Increase chances of finding a positive biomarker by moving from individual biomarker assays to a single comprehensive NGS assay

Streamlined Sample-to-Results Workflow

  • Go from initial sample to results in 4-5 days
  • Rapid variant calling algorithm powered by DRAGEN Bio-IT Platform, available locally on DRAGEN server
  • Secure, scalable, cloud-based variant analysis is available with DRAGEN pipelines on Illumina Connected Analytics (ICA)

High Sample Throughput

  • Flexible sample batching allows you to run anywhere from 16 to 192 samples per sequencing flow cell on the NovaSeq 6000 System.
  • Automation kits and methods available for reduced hands-on time and scalability*
  • Easily translate TruSight Oncology 500 raw data into a final interpretation report, powered by Pierian Clinical Genomics Workspace (CGW) software

Achieve Highly Confident Results

  • Hybrid-capture chemistry combined with sophisticated bioinformatics, leading to high analytical specificity and sensitivity
  • Inclusive of unique molecular indexes (UMIs) for high sensitivity in variant detection
  • Based on proven Illumina SBS sequencing technology

Enable In-House Comprehensive Genomic Profiling

  • Keep samples and data in house, for more control and ability to build a database
  • A future-proof assay with emerging biomarkers already included
Learn more about the TruSight Oncology Product Family

*Automation available on the Beckman Coulter i-Series or the Hamilton Microlab STAR. Contact Illumina Sales for more information.

TruSight Oncology 500 Portfolio

All three TruSight Oncology 500 assays are designed to identify key biomarkers in guidelines and clinical trials.

TruSight Oncology 500 Assay

Assess key cancer biomarkers from FFPE tumor tissue with the TruSight Oncology 500 Assay.

TruSight Oncology 500 High-Throughput Assay

Batch up to 192 samples at a time while using the same biomarkers and tissue type as the TruSight Oncology 500 assay.

TruSight Oncology 500 ctDNA Assay

Analyze circulating tumor DNA from plasma with the TruSight Oncology 500 ctDNA assay.

よく一緒に購入される製品

仕様

製品比較

TruSight Oncology 500 High-Throughput TruSight Oncology 500 TruSight Oncology 500 ctDNA
Cancer Type Pan-Cancer Pan-Cancer Pan-Cancer
Content Specifications Targeted selection of DNA from 523 genes of interest, and RNA from 55 genes, for a total of 1.94Mb panel size.
• Immuno-oncology Biomarker Coverage: TMB and MSI
• Guideline Coverage: Broad coverage of key guidelines for multiple solid tumor types
• Clinical Trials Coverage: Over 600 clinical trials*
Hands-On Time Manual: ~10.5 hrs
Automated: ~2.5 hrs
Input Quantity 40 ng DNA, 40-80 ng RNA (need at least 2 mm3 FFPE tissue)
Sample Throughput 16–192 samples per flow cell

Based on Pierian clinical knowledgebase, as of February 2023.

NovaSeq 6000Dx System in RUO Mode requires a separate, stand-alone DRAGEN server for secondary analysis.

Method-Specific Workflow Example

Supporting Data and Figures

 

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