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TruSight Oncology 500 to Power Liquid Biopsy Studies

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Variant calling for TruSight Oncology 500 HT is now more streamlined in the cloud with data streaming and auto-launch capabilities for the DRAGEN pipeline (v2.1) in Illumina Connected Analytics (ICA).

TruSight Oncology 500 High-Throughput

FFPEサンプルから、フローセルあたり一回192サンプルまで解析できる新たな柔軟性を備え、包括的なゲノムプロファイリングを実現します。続きを読む...

この製品は出荷できる国が制限されています。出荷の可否を確認するには、出荷する国を選択してください。

製品の選択

価格

Manual Prep

TruSight Oncology 500 DNA High-Throughput Kit (48 Samples)

20040765

価格

TruSight Oncology 500 DNA High-Throughput Kit (144 Samples)

20040767

価格

TruSight Oncology 500 DNA/RNA High-Throughput Kit (24 Samples)

20040764

価格

TruSight Oncology 500 DNA/RNA High-Throughput Kit (72 Samples)

20040766

価格

TruSight Oncology 500 DNA/RNA High-Throughput Kit (24 Samples), plus Pierian

20040768

価格

TruSight Oncology 500 DNA High-Throughput Kit (48 Samples), plus Pierian

20040769

価格

TruSight Oncology 500 DNA/RNA High-Throughput Kit (72 Samples), plus Pierian

20040770

価格

TruSight Oncology 500 DNA High-Throughput Kit (144 Samples), plus Pierian

20040771

価格

Automation

TruSight Oncology 500 High-Throughput DNA for Automation (64 Samples)

20049283

価格

TruSight Oncology 500 High-Throughput DNA/RNA for Automation (32 Samples)

20049282

価格

TruSight Oncology 500 High-Throughput DNA for Automation (64 Samples), Plus Pierian

20049277

価格

TruSight Oncology 500 High-Throughput DNA/RNA for Automation (32 Samples), Plus Pierian

20049276

価格

TruSight Oncology 500 High-Throughput DNA for Automation (144 Samples)

20049285

価格

TruSight Oncology 500 High-Throughput DNA for Automation (144 Samples), Plus Pierian

20049279

価格

TruSight Oncology 500 High-Throughput DNA/RNA for Automation (72 Samples)

20049284

価格

TSO500 DNA/RNA HT Auto (72 spls) + Pierian

20049278

価格

Index Adapters

IDT® for Illumina® UMI DNA/RNA UD Indexes Set A, Ligation (96 Indexes, 96 Samples)

20034701

価格

IDT® for Illumina® UMI DNA/RNA UD Indexes Set B, Ligation (96 Indexes, 96 Samples)

20034702

価格

IDT for Illumina UMI DNA/DNA Index Anchors Set A for Automation

20066404

価格

IDT for Illumina UMI DNA/RNA Index Anchors Set B for Automation

20063213

価格

Reagents

NovaSeq 6000 S4 Reagent Kit v1.5 (200 cycles)

20028313

価格

NovaSeq 6000 S2 Reagent Kit v1.5 (200 cycles)

20028315

価格

NovaSeq 6000 S1 Reagent Kit v1.5 (200 cycles)

20028318

価格

NovaSeq 6000 SP Reagent Kit v1.5 (200 cycles)

20040719

価格

Services

Trusight Oncology 500 HT Training (DNA) - Customer Site

20042220

価格

Trusight Oncology 500 HT Training (DNA and RNA) - Customer Site

20042219

価格

Software and Informatics Options

Illumina DRAGEN Server v3

20040619

価格

Illumina DRAGEN Server v4

20051343

価格

ICA Basic Annual Subscription

20044874

お問い合わせ

ICA Professional Annual Subscription

20044876

お問い合わせ

ICA Enterprise Annual Subscription

20038994

お問い合わせ

ICA Enterprise Service and Compliance Add-on (applies to Basic only)

20066830

お問い合わせ

Illumina Analytics - 1 iCredit

20042038

価格

Illumina Analytics Starter Package - 1,000 iCredits

20042039

価格

Illumina Analytics - 5,000 iCredit

20042040

価格

Illumina Analytics - 50,000 iCredit

20042041

価格

Illumina Analytics - 100,000 iCredit

20042042

価格

カートに追加

合計：

製品のハイライト

The TruSight Oncology 500 High-Throughput assay is built on the foundation of the TruSight Oncology 500 assay, with flexibility for higher sample throughput and batching options.

Consolidate Multiple Biomarker Assays into One

Pan-cancer biomarker content aligned with key guidelines and clinical trials
DNA + RNA assay targeting 523 genes for assessment of all DNA and RNA variant types, plus MSI and TMB
Increase chances of finding a positive biomarker by moving from individual biomarker assays to a single comprehensive NGS assay

Streamlined Sample-to-Results Workflow

Go from initial sample to results in 4-5 days
Rapid variant calling algorithm powered by DRAGEN Bio-IT Platform, available locally on DRAGEN server
Secure, scalable, cloud-based variant analysis is available with DRAGEN pipelines on Illumina Connected Analytics (ICA)

High Sample Throughput

Flexible sample batching allows you to run anywhere from 16 to 192 samples per sequencing flow cell on the NovaSeq 6000 System.

Automation kits and methods available for reduced hands-on time and scalability*
Easily translate TruSight Oncology 500 raw data into a final interpretation report, powered by Pierian Clinical Genomics Workspace (CGW) software

Achieve Highly Confident Results

Hybrid-capture chemistry combined with sophisticated bioinformatics, leading to high analytical specificity and sensitivity
Inclusive of unique molecular indexes (UMIs) for high sensitivity in variant detection
Based on proven Illumina SBS sequencing technology

Enable In-House Comprehensive Genomic Profiling

Keep samples and data in house, for more control and ability to build a database
A future-proof assay with emerging biomarkers already included

Learn more about the TruSight Oncology Product Family

^*Automation available on the Beckman Coulter i-Series or the Hamilton Microlab STAR. Contact Illumina Sales for more information.

TruSight Oncology 500 Portfolio

All three TruSight Oncology 500 assays are designed to identify key biomarkers in guidelines and clinical trials.

TruSight Oncology 500 Assay

Assess key cancer biomarkers from FFPE tumor tissue with the TruSight Oncology 500 Assay.

TruSight Oncology 500 High-Throughput Assay

Batch up to 192 samples at a time while using the same biomarkers and tissue type as the TruSight Oncology 500 assay.

TruSight Oncology 500 ctDNA Assay

Analyze circulating tumor DNA from plasma with the TruSight Oncology 500 ctDNA assay.

よく一緒に購入される製品

仕様

製品比較

	TruSight Oncology 500 High-Throughput	TruSight Oncology 500	TruSight Oncology 500 ctDNA
Cancer Type	Pan-Cancer	Pan-Cancer	Pan-Cancer
Content Specifications	Targeted selection of DNA from 523 genes of interest, and RNA from 55 genes, for a total of 1.94Mb panel size. • Immuno-oncology Biomarker Coverage: TMB and MSI • Guideline Coverage: Broad coverage of key guidelines for multiple solid tumor types • Clinical Trials Coverage: Over 600 clinical trials*
Hands-On Time	Manual: ~10.5 hrs Automated: ~2.5 hrs
Input Quantity	40 ng DNA, 40-80 ng RNA (need at least 2 mm³ FFPE tissue)
Sample Throughput	16–192 samples per flow cell

^*Based on Pierian clinical knowledgebase, as of February 2023.

^† NovaSeq 6000Dx System in RUO Mode requires a separate, stand-alone DRAGEN server for secondary analysis.

Prepare Library for:

TruSight Oncology 500 DNA High-Throughput Assay

Sequence Efficiently with:

NovaSeq 6000 System

Analyze Your Data with:

Variant Calling:

DRAGEN Bio-IT Platform: on-premise via DRAGEN server

DRAGEN Bio-IT Platform: cloud-based via Illumina Connected Analytics, ICA

TruSight Oncology 500 Local App: Docker-based Software

Interpretation & Reporting:

Compatible with Pierian Clinical Genomics Workspace Software

High concordance of TMB status between DRAGEN TruSight Oncology v2 and Local App

High concordance of MSI status between DRAGEN TruSight Oncology v2 and Local App

High concordance of CNV (Gene Amplification) detection between DRAGEN TruSight Oncology v2 and Local App

High concordance of SNVs with mean VAF >5% between DRAGEN TruSight Oncology v2 and Local App

Robust detection of fusions and splice variants

Fusion and splice variants as detected using TruSight Oncology 500 o the NextSeq 500 System. Numeric values represent the number of supporting reads for each sample at the indicated RNA input amount. Cut-off value for RNA fusions = 5; cut-off value for splice variants = 10.