The TruSight Hereditary Cancer Panel content was selected based on feedback from key opinion leaders on genetic risk assessment.
TruSight Hereditary Cancer Panel was created as a modular panel that uses Nextera Flex for Enrichment (NFE) for library preparation.
Indexes are available for up to 384 samples to allow for flexible batch sizes and scalability across all Illumina benchtop sequencers (iSeq 100, MiSeq, MiniSeq, and NextSeq).
The Nextera Flex for Enrichment library prep workflow uses enzyme-based DNA fragmentation, removing the instrument cost and need for mechanical fragmentation. Nextera Flex for Enrichment has been qualified with multiple automation systems to allow for a user-friendly workflow.
TruSight Hereditary Cancer Panel | TruSight Cancer | AmpliSeq for Illumina BRCA Panel | |
---|---|---|---|
Assay Time | ~6.5 hours | 1.5 days | 5 hours (library prep only; doesn't include library quantification, normalization, or pooling time) |
Method | Target Enrichment, Target Enrichment, Targeted DNA Sequencing | Target Enrichment, Target Enrichment, Targeted DNA Sequencing | Amplicon Sequencing, Targeted DNA Sequencing |
Nucleic Acid Type | DNA | DNA | DNA |
Technology | Sequencing | Sequencing | Sequencing |
Understanding the Polygenicity of Cancer.
icommunity_articles | PDF 4 MB
Data Sheet | HTML | 7 versions
Data Sheet | HTML | 5 versions
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