製品

TruSight Hereditary Cancer Panel

Expert-defined content targeting 113 genes associated with genetic cancer risk predisposition.Read More...
製品の選択
What products do I need?

TruSight Hereditary Cancer Panel - Enrichment Oligos only (8 Enrichment Reactions)

20029551

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Nextera DNA Flex Pre-Enrichment Library Prep and Enrichment Reagents - 96 samples (8, 12-plex enrichment reactions)

20025524

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Nextera DNA Flex Pre-Enrichment Library Prep and Enrichment Reagents - 16 samples (16, 1-plex enrichment reactions)

20025523

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Nextera DNA Flex Pre-Enrichment Library Prep Reagents (96 samples)

20025520

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Nextera DNA Flex Pre-Enrichment Library Prep Reagents (16 samples)

20025519

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Index Adapters

IDT® for Illumina Nextera DNA Unique Dual Indexes Set A (96 Indexes, 96 Samples)

20027213

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IDT® for Illumina Nextera DNA Unique Dual Indexes Set B (96 Indexes, 96 Samples)

20027214

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IDT® for Illumina Nextera DNA Unique Dual Indexes Set C (96 Indexes, 96 Samples)

20027215

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IDT® for Illumina Nextera DNA Unique Dual Indexes Set D (96 Indexes, 96 Samples)

20027216

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IDT® for Illumina Nextera DNA Unique Dual Indexes Sets A-D (384 Indexes, 384 Samples)

20027217

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Sequencing Consumables

iSeq 100 i1 Reagent

20021533

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iSeq 100 i1 Reagent 4 pack

20021534

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MiSeq Reagent Micro Kit v2 (300-cycles)

MS-103-1002

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MiSeq Reagent Kit v2 (300-cycles)

MS-102-2002

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MiSeq Reagent Kit v3 (600-cycle)

MS-102-3003

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MiniSeq Mid Output Kit (300-cycles)

FC-420-1004

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MiniSeq High Output Reagent Kit (300-cycles)

FC-420-1003

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NextSeq 500/550 Mid Output Kit v2.5 (300 Cycles)

20024905

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NextSeq 500/550 High Output Kit v2.5 (300 Cycles)

20024908

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アクセサリー製品
What accessories do I need?

Flex Lysis Reagent Kit 96 reactions

20018706

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TruSight Hereditary Cancer Panel

Product Highlights

The TruSight Hereditary Cancer Panel content was selected based on feedback from key opinion leaders on genetic risk assessment.

  • Includes 10,341 probes that target 113 genes related to cancer predisposition.
  • TruSight Hereditary Cancer Panel includes 125 SNPs. Of these, 48 are ID SNPs and 77 are used for polygenic risk scoring (PRS).
  • In combination with Nextera Flex for Enrichment, TruSight Hereditary Cancer Panel enables genetic labs to prepare hybrid capture sequencing libraries in 6.5 hours with limited hands on time of ~2 hours.
  • Accommodates flexible workflows and is compatible with different sources of samples such as genomic DNA, saliva (Oragene tubes) or blood (Flex Lysis Reagent). It is compatible with all Illumina benchtop sequencers, and allows for maximum flexibility for batching from 2 to 256 samples.

TruSight Hereditary Cancer Panel was created as a modular panel that uses Nextera Flex for Enrichment (NFE) for library preparation.

Indexes are available for up to 384 samples to allow for flexible batch sizes and scalability across all Illumina benchtop sequencers (iSeq 100, MiSeq, MiniSeq, and NextSeq).

The Nextera Flex for Enrichment library prep workflow uses enzyme-based DNA fragmentation, removing the instrument cost and need for mechanical fragmentation. Nextera Flex for Enrichment has been qualified with multiple automation systems to allow for a user-friendly workflow.

Frequently Purchased Together

仕様

製品比較

TruSight Hereditary Cancer Panel TruSight Cancer AmpliSeq for Illumina BRCA Panel
Assay Time ~6.5 hours 1.5 days 5 hours (library prep only; doesn't include library quantification, normalization, or pooling time)
Automation Capability Liquid Handling Robots
Nucleic Acid Type DNA DNA DNA
System Compatibility iSeq 100 , MiniSeq , MiSeq , MiSeqDx in Research Mode , NextSeq 500 , NextSeq 550 , NextSeq 550Dx in Research Mode MiniSeq , MiSeq , MiSeqDx in Research Mode , NextSeq 500 , NextSeq 550 iSeq 100 , MiniSeq , MiSeq , MiSeqDx in Research Mode
Technology Sequencing Sequencing Sequencing
Variant Class Copy Number Variants (CNVs), Germline Variants, Insertions-Deletions (indels) Germline Variants Germline Variants, Insertions-Deletions (indels), Single Nucleotide Polymorphisms (SNPs), Somatic Variants

Method-Specific Workflow Example

 
Prepare Library for:
Nextera Flex for Enrichment
IDT for Illumina Nextera DNA UD Indexes
 
Sequence Efficiently with:
iSeq 100 System
MiniSeq System
MiSeq System
NextSeq 550 System
 
Analyze Your Data with:
DRAGEN Enrichment
BaseSpace Enrichment
 

製品に関する文献

Nextera Flex for Enrichment Data Sheet

Data Sheet | HTML

TruSight Hereditary Cancer Panel Data Sheet

Data Sheet | HTML

マニュアルとサポート情報

カスタムプロトコルセレクタ
Generates customized, end-to-end instructions

すべて Nextera Flex for Enrichment Support Resources Support 

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